3D pharmacophore model studies on ACRB efflux pump inhibitors of Escherichia coli : Bachelor Theses

dc.date.accessioned	2025-06-13T09:17:45Z
dc.date.available	2025-06-13T09:17:45Z
dc.date.issued	2020
dc.description	47 p.
dc.description.abstract	Resistance to antibiotics poses a major global threat according to the World Health Organization. There are various ways in which bacterium can develop its resistance to an antibiotic and efflux pump is one of the major mechanisms. AcrB of Escherichia coli is the main efflux pump. Hence, efflux pump inhibitors (EPIs) is a promising strategy to restore antibacterial potency. This study focuses on potential inhibitors of AcrB on Escherichia coli. The virtual screening approach built in this study is 3D-pharmacophore, which is used to screen potential inhibitors that are studied in laboratory.
dc.identifier.uri	https://repository.ntt.edu.vn/handle/298300331/409
dc.language.iso	en
dc.publisher	Nguyen Tat Thanh University
dc.subject	Escherichia coli
dc.subject	3D pharmacophore
dc.subject	ACRB efflux pump inhibitors
dc.title	3D pharmacophore model studies on ACRB efflux pump inhibitors of Escherichia coli : Bachelor Theses
dc.type	Thesis