Study hydrogel containing papain extracted from Carica papaya L. for wound healing : Graduation Thesis
Năm xuất bản
2023
Tác giả
Nhan đề tạp chí
ISSN
Nhan đề tập
Nhà xuất bản
Nguyen Tat Thanh University (Faculty Of Pharmacy)
Tóm tắt
This study focused on formulating and characterizing hydrogel films containing papain, an enzyme extracted and purified from ripe papaya latex. Papain demonstrated enzymatic activity (0.0749 U/mg) and was incorporated into HPMC-based hydrogels using a microwave-assisted crosslinking method. The resulting films had a thickness of 0.8 mm, moisture content of 3.83%, and showed a sustained papain release of 2.67% to 5.10% over 60 minutes. FTIR and FESEM analyses confirmed the successful incorporation and distribution of papain within the films. These findings highlight the potential of papain-loaded hydrogels for controlled drug release and enhanced wound healing applications.
Mô tả
51 p.
Từ khóa chủ đề
Carica papaya L., Papain Extracted, Hydrogel, Wound healing