2D-QSAR studies on MexAB-OprM efflux pump inhibitors of Pseudomonas aeruginos :  Bachelor Theses

dc.contributor.advisor	Phan, Thien Vy (M.S Pharm.)
dc.contributor.author	Nguyen, Truong Khanh Vy
dc.date.accessioned	2025-06-13T09:15:10Z
dc.date.available	2025-06-13T09:15:10Z
dc.date.issued	2020
dc.description	54 p.
dc.description.abstract	These days, the rate of antimicrobial resistance (AMR) in Gram-Negative bacteria is increasing rapidly. According to an exhaustive review commissioned by UK government, globally, approximately 700,000 deaths can be attributed to AMR each year. Hence, efflux pump has been found to be related multi-drug resistance in clinical isolate as well as MexAB-OprM. MexAB-OprM is the most important multi-drug efflux system of P. aeruginosa due to the wide resistance on antibiotics. Many studies discovered efflux pump inhibitors (EPIs) that are able to combine with antibiotics, which is one of the most potential therapies. Thus, the main point of this study is to build a 2D–QSAR models, which have predictive capabilities for efflux pump inhibitory activities of natural compounds and clinical medicines.
dc.identifier.uri	https://repository.ntt.edu.vn/handle/298300331/408
dc.language.iso	en
dc.publisher	Nguyen Tat Thanh University
dc.subject	2D-QSAR
dc.subject	MexAB-OprM
dc.subject	Pseudomonas aeruginos
dc.title	2D-QSAR studies on MexAB-OprM efflux pump inhibitors of Pseudomonas aeruginos : Bachelor Theses
dc.type	Thesis