Application of machine learning models for green and simultaneous determination of asiaticoside and madecassoside in Centella asiatica

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dc.contributor.authorTa, Thi Thao
dc.contributor.authorNguyen, Dieu Linh
dc.contributor.authorNguyen, Thi Ha Ly
dc.contributor.authorHoang, Thi Tuyet
dc.contributor.authorDo Thi Ha
dc.date.accessioned2024-08-21T02:41:27Z
dc.date.accessioned2024-08-29T02:21:12Z
dc.date.available2024-08-21T02:41:27Z
dc.date.available2024-08-29T02:21:12Z
dc.date.issued2024
dc.description8 p.
dc.description.abstractThe artificial neuron network (ANN), which is a subfield of machine learning, has been widely applied in analytical chemistry for classification/pattern recognition, prediction, and modeling. ANN combined with UV spectrometry can be used to tackle the problem of overlapping spectra of a complicated matrix of herbal medicine. In the present study, ANN has been used for simultaneous determination of asiaticoside and madecassoside in Centella asiatica collected from various provinces in Viet Nam based on UV spectra of standard reference and spiked samples. The absorption spectra of 108 C. asiatica samples were recorded in (190-250) nm of wavelength with an interval of 1 nm (61 variables) were used for data acquisition. An ANN model using traincgb function with 40 neural hidden layers was trained. The correlation coefficients were all higher than 0.9999. The concentration of asiaticoside and madecassoside in all tested samples revealed a good recovery, as compared to the referenced values. The ANN model can be considered as effective, time-saving and environment-friendly quantitative analysis tool for herbal medicine.
dc.identifier.citationNguyen Tat Thanh University. (2024). Journal of Science and Technology - NTTU, Volume 7, Issue 1. ISSN 2615-9015.
dc.identifier.issn2615-9015
dc.identifier.urihttps://repository.ntt.edu.vn/handle/298300331/50092
dc.language.isoen
dc.publisherNguyen Tat Thanh University
dc.relation.ispartofseriesJournal of Science and Technology - NTTU; Vol.7, No. 1
dc.subjectArtificial Neural
dc.subjectNetwork (ANN)
dc.subjectSimultaneous
dc.subjectDetermination
dc.subjectMachine learning
dc.subjectUV spectrophotometry
dc.subjectCentella asiatica
dc.subjectMạng nơron nhân tạo
dc.subjectQuang phổ UV
dc.titleApplication of machine learning models for green and simultaneous determination of asiaticoside and madecassoside in Centella asiatica
dc.typeArticle

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