3D-Pharmacophore model studies on MexB efflux pump inhibitor of Pseudomonas aeruginosa :  Bachelor Theses

dc.contributor.advisor	Phan, Thien Vy (M.S. Pharm.)
dc.contributor.author	Dinh, Nguyen Thuy Duyen
dc.date.accessioned	2025-06-13T09:11:18Z
dc.date.available	2025-06-13T09:11:18Z
dc.date.issued	2020
dc.description	50 p.
dc.description.abstract	In recent years, antimicrobial resistance rates in gram-negative bacteria are increasing rapidly and efflux pump has been found to be related to multi-drug resistance in clinical isolates. MexAB-OprM tripartite efflux pump, which belongs to the RND superfamily, are the main multi-drug efflux system of Pseudomonas aeruginosa because of the broad resistance on antibiotics. With the discovering of efflux pump inhibitors (EPIs), the combination between these and antibiotics is one of the most promising therapies. Therefore, the main research direction focuses on developing MexAB-OprM pump inhibitors to restore antibiotic activity.
dc.identifier.uri	https://repository.ntt.edu.vn/handle/298300331/407
dc.language.iso	en
dc.publisher	Nguyen Tat Thanh University
dc.subject	Pseudomonas aeruginosa
dc.subject	3D-Pharmacophore
dc.subject	MexB efflux
dc.title	3D-Pharmacophore model studies on MexB efflux pump inhibitor of Pseudomonas aeruginosa : Bachelor Theses
dc.type	Thesis

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