Synthesis of Hydroxychavicol from Eugenol : Graduations Thesis

dc.contributor.advisor	Phan, Minh Hoang (M.S.)
dc.contributor.author	Tran, Thanh Ngoc
dc.date.accessioned	2025-06-25T07:11:21Z
dc.date.available	2025-06-25T07:11:21Z
dc.date.issued	2023
dc.description	70 p.
dc.description.abstract	Hydroxychavicol, a compound with multiple biological activities such as anti-inflammatory, antioxidant, and anticancer effects, was successfully synthesized from eugenol at the laboratory scale. The optimal demethylation conditions involved AlCl₃ and pyridine in acetonitrile, yielding up to 89%. Structural confirmation was performed by MS and NMR, and product purity reached 97.113% (GC-MS). This synthesis lays the foundation for scaling up and exploring hydroxychavicol derivatives.
dc.identifier.uri	https://repository.ntt.edu.vn/handle/298300331/452
dc.language.iso	vi_VN
dc.publisher	Trường Đại học Nguyễn Tất Thành (Khoa Dược)
dc.subject	Eugenol
dc.subject	Hydroxychavicol
dc.subject	Khử methyl
dc.subject	Phổ khối (MS)
dc.subject	Phổ cộng hưởng từ hạt nhân (NMR)
dc.subject	Sắc ký khí – khối phổ (GC-MS)
dc.subject	Demethylation
dc.subject	Optimization
dc.title	Synthesis of Hydroxychavicol from Eugenol : Graduations Thesis
dc.type	Article