Cytotoxic activity of Combretum quadrangulare leaf extracts on HepG2 cancer cell line
| dc.contributor.author | Thi-Phuong Nguyen | |
| dc.contributor.author | Thuc-Huy Duong | |
| dc.contributor.author | Huu-Hung Nguyen | |
| dc.date.accessioned | 2024-08-20T08:39:16Z | |
| dc.date.accessioned | 2024-08-29T02:16:43Z | |
| dc.date.available | 2024-08-20T08:39:16Z | |
| dc.date.available | 2024-08-29T02:16:43Z | |
| dc.date.issued | 2018 | |
| dc.description | 3 p. | |
| dc.description.abstract | Studies on anticancer using plant extracts/compounds are promising. However, information regarding in vitro cytotoxicity is incompleted. Herein, this study aims to evaluate the cytotoxicity potentials of hexan:ethyl acetate (50:50, v:v) and ethanol extracts of Combretum quadrangulare leaves on HepG2 cancer cell line. Using cell viablity MTT assay, hexan: ethyl acetate and ethanol extracts were defined as potential cytotoxicity with IC50 at 38 and 47 µg/mL respectively. In addition, by microscopy observation, we found that morphology of the cells apparently change in a dose and time dependent manner. The data showed in this study shed new light for further investigation of the anticancer effect of C. quadrangulare extracts and its compounds. | |
| dc.identifier.citation | Trường Đại học Nguyễn Tất Thành. (2018). Tạp chí Khoa học và Công nghệ - Đại học Nguyễn Tất Thành [Journal of Science and Technology - NTTU], (01). ISSN 2615-9015 | |
| dc.identifier.issn | 2615-9015 | |
| dc.identifier.uri | https://repository.ntt.edu.vn/handle/298300331/50158 | |
| dc.language.iso | vi_VN | |
| dc.publisher | Nguyen Tat Thanh University | |
| dc.relation.ispartofseries | Journal of Science and Technology - NTTU; No. 01 | |
| dc.subject | Combretum quadrangulare | |
| dc.subject | Extract | |
| dc.subject | Cytotoxicity | |
| dc.subject | HepG2 | |
| dc.subject | MTT | |
| dc.subject | Dòng tế bào ung thư HepG2 | |
| dc.title | Cytotoxic activity of Combretum quadrangulare leaf extracts on HepG2 cancer cell line | |
| dc.type | Article |