Duyệt theo Tác giả "Tran, Thanh Ngoc"
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Tài liệu Synthesis of Hydroxychavicol from Eugenol : Graduations Thesis(Trường Đại học Nguyễn Tất Thành (Khoa Dược), 2023) Tran, Thanh Ngoc; Phan, Minh Hoang (M.S.)Hydroxychavicol, a compound with multiple biological activities such as anti-inflammatory, antioxidant, and anticancer effects, was successfully synthesized from eugenol at the laboratory scale. The optimal demethylation conditions involved AlCl₃ and pyridine in acetonitrile, yielding up to 89%. Structural confirmation was performed by MS and NMR, and product purity reached 97.113% (GC-MS). This synthesis lays the foundation for scaling up and exploring hydroxychavicol derivatives.